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Webinar – Raman technology to enable real-time upstream bioprocess monitoring of CPPs and CQAs and continuous control: From media preparation to cell culture expansion

September 5, 2023
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Date: September 5th, 2023

Time:
11 AM (CET)

Title: Webinar – Raman technology to enable real-time upstream bioprocess monitoring of CPPs and CQAs and continuous control: From media preparation to cell culture expansion

Description:

Raman spectroscopy is widely acknowledged as a crucial component of the Process Analytical Technology (PAT) approach in bioprocessing, which is aimed at ensuring predefined product quality and performance standards. This study showcases Raman technology in combination with chemometrics as an effective solution for in-line and real-time monitoring of critical process parameters (CPPs) and critical quality attributes (CQAs) in the upstream process (USP) of bioprocessing. The solution provides a complete understanding of the process by enabling multi-factorial monitoring. It ensures the quality control of the cell culture media preparation while also enabling an automated feeding strategy that ensures precise control of the cell expansion process. Moreover, real-time monitoring of the glycosylation profiles serves to confirm that product quality standards are met.

Speaker

Name:
Mr. Hadi EL Radi

Position:
PAT Implementation & Support Engineer

Biography:

His expertise is in the Chemometrics area with a Master’s degree focused on Analytical Chemistry, Chemometrics, Process Optimization, and Quality Control.

He has extensive experience in building accurate, robust, reliable, and transferable models for NIR and Raman Spectroscopy sensors to solve various industries’ needs. In his role, he has fully dedicated to the Raman technology applied to Life Science with the aim to raise awareness about the benefits of this technology, facilitating its implementation, and showcasing its capabilities to solve industry needs.

Documents
One Pager Report - Merck KGaA, Darmstadt, Germany
Merck KGaA, Darmstadt, Germany - Webinar